What is ICSI?
- ICSI stands for Intracytoplasmic Sperm Injection. IVF with ICSI starts with egg collection and then involves injecting a single sperm into the center of each mature egg, to help fertilization to occur.
- The resulting embryos are transferred to the female womb in the same way as in a conventional IVF cycle. The extra embryos that are not transferred in this cycle can be frozen for the future use.
- Most of the time, the ICSI treatment result in the most successful way for men who are infertile.
Who needs ICSI?
ICSI is used, in synchronicity, with an IVF cycle when fertilization is unlikely to occur using conventional IVF.
Most commonly, ICSI is appropriate when there is a male factor to your infertility. ICSI is mainly used in the following case:
- The number of sperm is low.
- The sperm motility (movement) is poor.
- There is a high number of abnormal sperm.
- The sperm has been collected surgically.
- There are high levels of antibodies in the semen.
- There have been past unexplained failures to achieve fertilization in conventional IVF, or when very few eggs have fertilized following IVF.
- Sperm function tests have revealed that the sperm would be questionable to achieve fertilization, or embryo quality and implantation may be compromised.
- Donated gametes are being used.
What is the necessary treatment procedure?
ICSI process involves the following steps:
- The mature egg is held with a particular holding pipette.
- With a very fine, sharp and hollow needle, a single sperm is collected.
- Then the needle is delicately inserted into the shell of the egg (zona) and the cytoplasm (center) of the egg.
- The sperm is implanted into the cytoplasm, and the needle is removed.
- One has to wait till next morning to see the ICSI treatment result i.e. the examination of eggs for any evidence of regular fertilization.